VEGF-VEGFR signaling pathway
Schematic diagram of VEGF-VEGFR signaling pathway. The members of the VEGF family include VEGFA, VEGFB, VEGFC, VEGFD, VEGFE, and PlGF. VEGFA has an important role in regulating the normal body and disease-related angiogenesis. VEGFB, PIGF, and VEGFA combine with VEGFR-1; VEGFA, VEGFC, and VEGFE combine with VEGFR-2; VEGFC and VEGFD combine with VEGFR-3. The VEGFR-1 and VEGFR-2 systems are responsible for angiogenesis, while VEGFR-3 is responsible for the angiogenesis of both blood vessels and lymphatics
Publication
Vascular Endothelial Growth Factor A VEGFA Inhibition: An Effective Treatment Strategy for Psoriasis (2024) Ya Chen, et al. Int J Mol Sci. 2024 Jan;25(1). Figure: F2.| Organism | Group | Word | Match | Source | NCBI Symbol | NCBI ID |
|---|---|---|---|---|---|---|
| Homo sapiens | Primates | VEGFB | VEGFB | ncbigene_symbol | VEGFB | 7423 |
| Homo sapiens | Primates | VEGFA | VEGFA | ncbigene_symbol | VEGFA | 7422 |
| Homo sapiens | Primates | PIGF | PIGF | ncbigene_symbol | PIGF | 5281 |
| Homo sapiens | Primates | PIGF | PIGF | ncbigene_synonym | PGF | 5228 |
| Homo sapiens | Primates | VEGFC | VEGFC | ncbigene_symbol | VEGFC | 7424 |
| Homo sapiens | Primates | VEGFR-1 | VEGFR-1 | ncbigene_synonym | FLT1 | 2321 |
| Homo sapiens | Primates | VEGFR-2 | VEGFR2 | ncbigene_synonym | KDR | 3791 |
| Homo sapiens | Primates | VEGFD | VEGFD | ncbigene_symbol | VEGFD | 2277 |
| Homo sapiens | Primates | VEGFR-3 | VEGFR-3 | ncbigene_synonym | FLT4 | 2324 |
| Word | Match | MeSH | Name | ChEBI |
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Disease mentions
| Word | Match | MeSH | Name | DOID |
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