Protein interaction network created using STRING database based on Bos taurus genome

Protein interaction network created using STRING database based on Bos taurus genome. Edges represent protein–protein associations, line thickness indicates the strength of the supporting data, network nodes represent proteins, and colors indicate their functional categories: GO database—dark blue—GO:0032481 “Positive regulation of type I interferon production” (FDR = 9.69 × 10−13); green—GO:0002764 “Immune response-regulating signaling pathway” (FDR = 9.76 × 10−12); grey—GO:1901222 “Regulation of NIK/NF-kappaB signaling” (FDR = 3.33 × 10−6); KEEG-pathways—light blue—bta04620 “Toll-like receptor signaling pathway” (FDR = 1.53 × 10−32); pink—bta04621 “NOD-like receptor signaling pathway” (FDR = 3.48 × 10−16); yellow—bta04060 “Cytokine–cytokine receptor interaction (FDR = 8.74 × 10−9); light green—bta04612 “Antigen processing and presentation (FDR = 0.0187)

Publication

An Outbred Calf Model for Determining Innate Immune Sensing and Evolutionary Trajectories of a Cell Culture-Adapted Bovine Foamy Virus Variant (2023) Magdalena Materniak-Kornas, et al. Viruses. 2023 Aug;15(8). Figure: F5. Homo sapiens

Disease mentions