Oxidative stress promotes the activation of programmed cell death initiated by intrinsic apoptotic signaling in the mitochondria or extrinsic apoptotic signaling by death receptor pathways in CRC cells

Oxidative stress promotes the activation of programmed cell death initiated by intrinsic apoptotic signaling in the mitochondria or extrinsic apoptotic signaling by death receptor pathways in CRC cells. [Apaf 1, Apoptotic protease activating factor 1; BAD, Bcl-2-Associated agonist of cell death; BAX, Bcl-2-associated X protein; Bcl-2, B-cell lymphoma-2; BID, BH3-interacting domain death agonist; cyto c, cytochrome c; tBID, C-terminal fragment termed truncated Bid]
Oxidative stress promotes the activation of programmed cell death initiated by intrinsic apoptotic signaling in the mitochondria or extrinsic apoptotic signaling by death receptor pathways in CRC cells
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Publication

Different Roles of Apoptosis and Autophagy in the Development of Human Colorectal Cancer (2023) Giulia Orlandi, et al. Int J Mol Sci. 2023 Jun;24(12). Figure: F4.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Homo sapiens Primates Deathreceptor DEATHRECEPTOR famplex_relations TNFRSF1A 7132
Homo sapiens Primates Deathreceptor DEATHRECEPTOR famplex_relations TNFRSF1B 7133
Homo sapiens Primates Deathreceptor DEATHRECEPTOR famplex_relations TNFRSF10A 8797
Homo sapiens Primates Deathreceptor DEATHRECEPTOR famplex_relations TNFRSF10B 8795
Homo sapiens Primates Deathreceptor DEATHRECEPTOR famplex_relations TNFRSF10C 8794
Homo sapiens Primates Deathreceptor DEATHRECEPTOR famplex_relations TNFRSF10D 8793
Homo sapiens Primates Deathreceptor DEATHRECEPTOR famplex_relations FAS 355
Homo sapiens Primates caspase CASPASE famplex_relations CASP1 834
Homo sapiens Primates caspase CASPASE famplex_relations CASP2 835
Homo sapiens Primates caspase CASPASE famplex_relations CASP4 837
Homo sapiens Primates caspase CASPASE famplex_relations CASP5 838
Homo sapiens Primates caspase CASPASE famplex_relations CASP6 839
Homo sapiens Primates caspase CASPASE famplex_relations CASP8 841
Homo sapiens Primates caspase CASPASE famplex_relations CASP9 842
Homo sapiens Primates caspase CASPASE famplex_relations CASP10 843
Homo sapiens Primates caspase CASPASE famplex_relations CASP12 100506742
Homo sapiens Primates caspase CASPASE famplex_relations CASP14 23581
Homo sapiens Primates caspase CASPASE famplex_relations CASP3 836
Homo sapiens Primates caspase CASPASE famplex_relations CASP7 840
Homo sapiens Primates BID BID ncbigene_symbol BID 637
Homo sapiens Primates Bcl-2 BCL-2 ncbigene_synonym BCL2 596
Homo sapiens Primates BAD BAD ncbigene_symbol BAD 572
Homo sapiens Primates BAX,BAD BAX ncbigene_symbol BAX 581
Homo sapiens Primates p53 P53 ncbigene_synonym TP53 7157
Homo sapiens Primates p53 P53 famplex_relations TP63 8626
Homo sapiens Primates p53 P53 famplex_relations TP73 7161

Chemical mentions

Word Match MeSH Name ChEBI

Disease mentions

Word Match MeSH Name DOID