Signal pathways associated with lung adenocarcinoma
Signal pathways associated with lung adenocarcinoma. The blue nodes are the eight driver genes in the signaling pathway identified under k = 10. Rectangular nodes indicate a specific biological function, and the line between nodes indicates the interaction between them: the arrow indicates an activation relationship between the two nodes; the “T” connector line indicates an inhibitory relationship between the two nodes
Publication
Identifying Cancer Driver Pathways Based on the Mouth Brooding Fish Algorithm (2023) Wei Zhang, et al. Entropy (Basel). 2023 Jun;25(6). Figure: F3.| Organism | Group | Word | Match | Source | NCBI Symbol | NCBI ID |
|---|---|---|---|---|---|---|
| Homo sapiens | Primates | GSK3 | GSK3 | famplex_relations | GSK3A | 2931 |
| Homo sapiens | Primates | GSK3 | GSK3 | famplex_relations | GSK3B | 2932 |
| Homo sapiens | Primates | NF1 | NF1 | ncbigene_symbol | NF1 | 4763 |
| Homo sapiens | Primates | EGFR | EGFR | ncbigene_symbol | EGFR | 1956 |
| Homo sapiens | Primates | RAS | RAS | famplex_relations | KRAS | 3845 |
| Homo sapiens | Primates | RAS | RAS | famplex_relations | HRAS | 3265 |
| Homo sapiens | Primates | RAS | RAS | famplex_relations | NRAS | 4893 |
| Homo sapiens | Primates | AKT | AKT | ncbigene_synonym | AKT1 | 207 |
| Homo sapiens | Primates | AKT | AKT | famplex_relations | AKT2 | 208 |
| Homo sapiens | Primates | AKT | AKT | famplex_relations | AKT3 | 10000 |
| Homo sapiens | Primates | PI3K | PI3K | ncbigene_synonym | PIK3CA | 5290 |
| Homo sapiens | Primates | PI3K | PI3K | ncbigene_synonym | PIK3CB | 5291 |
| Homo sapiens | Primates | PI3K | PI3K | ncbigene_synonym | PIK3CD | 5293 |
| Homo sapiens | Primates | PI3K | PI3K | ncbigene_synonym | PIK3CG | 5294 |
| Homo sapiens | Primates | PI3K | PI3K | famplex_relations | PIK3R3 | 8503 |
| Homo sapiens | Primates | PI3K | PI3K | famplex_relations | PIK3R4 | 30849 |
| Homo sapiens | Primates | PI3K | PI3K | famplex_relations | PIK3R5 | 23533 |
| Homo sapiens | Primates | PI3K | PI3K | famplex_relations | PIK3R6 | 146850 |
| Homo sapiens | Primates | PI3K | PI3K | famplex_relations | PIK3R1 | 5295 |
| Homo sapiens | Primates | PI3K | PI3K | famplex_relations | PIK3R2 | 5296 |
| Homo sapiens | Primates | APC | APC | ncbigene_symbol | APC | 324 |
| Homo sapiens | Primates | APC | APC | ncbigene_synonym | PROC | 5624 |
| Homo sapiens | Primates | STK11 | STK11 | ncbigene_symbol | STK11 | 6794 |
| Homo sapiens | Primates | TSC1/2 | TSC1 | ncbigene_symbol | TSC1 | 7248 |
| Homo sapiens | Primates | TSC1/2 | TSC1 | ncbigene_synonym | CCL26 | 10344 |
| Homo sapiens | Primates | TSC1/2 | TSC2 | ncbigene_symbol | TSC2 | 7249 |
| Homo sapiens | Primates | MDM2 | MDM2 | ncbigene_symbol | MDM2 | 4193 |
| Homo sapiens | Primates | MTOR | MTOR | ncbigene_symbol | MTOR | 2475 |
| Homo sapiens | Primates | TP53 | TP53 | ncbigene_symbol | TP53 | 7157 |
| Homo sapiens | Primates | ATM | ATM | ncbigene_symbol | ATM | 472 |
| Word | Match | MeSH | Name | ChEBI |
|---|---|---|---|---|
| RAS | RAS | (1R)-N-(prop-2-yn-1-yl)indan-1-amine | chebi:63620 | |
| Protein | Protein | a protein | chebi:16541 |
Disease mentions
| Word | Match | MeSH | Name | DOID |
|---|