Involvement of ITGA and ITGB receptors in ‘focal adhesion’ and ‘ECM receptor interaction’ from the Kyoto Encyclopaedia of Genes and Genomes pathway database
Involvement of ITGA and ITGB receptors in ‘focal adhesion’ and ‘ECM receptor interaction’ from the Kyoto Encyclopaedia of Genes and Genomes pathway database. ECM, extracellular matrix. The figure was obtained from Kanehisa Laboratories.
Publication
SPTBN2 regulates endometroid ovarian cancer cell proliferation, invasion and migration via ITGB4‑mediated focal adhesion and ECM receptor signalling pathway (2023) La Yang, et al. Exp Ther Med. 2023 Jun;25(6). Figure: F5.| Organism | Group | Word | Match | Source | NCBI Symbol | NCBI ID |
|---|---|---|---|---|---|---|
| Homo sapiens | Primates | RhoGAP | RHOGAP | ncbigene_synonym | ARHGAP1 | 392 |
| Homo sapiens | Primates | RhoA | RHOA | ncbigene_symbol | RHOA | 387 |
| Homo sapiens | Primates | ROCK | ROCK | famplex_relations | ROCK1 | 6093 |
| Homo sapiens | Primates | ROCK | ROCK | famplex_relations | ROCK2 | 9475 |
| Homo sapiens | Primates | MLC | MLC | ncbigene_synonym | MLC1 | 23209 |
| Homo sapiens | Primates | MLCK | MLCK | ncbigene_synonym | MYLK | 4638 |
| Homo sapiens | Primates | MLCK | MLCK | ncbigene_synonym | MYLK2 | 85366 |
| Homo sapiens | Primates | MLCK | MLCK | ncbigene_synonym | MYLK3 | 91807 |
| Homo sapiens | Primates | VASP | VASP | ncbigene_symbol | VASP | 7408 |
| Homo sapiens | Primates | ITGA | ITGA | famplex_relations | ITGA1 | 3672 |
| Homo sapiens | Primates | ITGA | ITGA | famplex_relations | ITGA10 | 8515 |
| Homo sapiens | Primates | ITGA | ITGA | famplex_relations | ITGA11 | 22801 |
| Homo sapiens | Primates | ITGA | ITGA | famplex_relations | ITGA2 | 3673 |
| Homo sapiens | Primates | ITGA | ITGA | famplex_relations | ITGA2B | 3674 |
| Homo sapiens | Primates | ITGA | ITGA | famplex_relations | ITGA3 | 3675 |
| Homo sapiens | Primates | ITGA | ITGA | famplex_relations | ITGA4 | 3676 |
| Homo sapiens | Primates | ITGA | ITGA | famplex_relations | ITGA5 | 3678 |
| Homo sapiens | Primates | ITGA | ITGA | famplex_relations | ITGA6 | 3655 |
| Homo sapiens | Primates | ITGA | ITGA | famplex_relations | ITGA7 | 3679 |
| Homo sapiens | Primates | ITGA | ITGA | famplex_relations | ITGA8 | 8516 |
| Homo sapiens | Primates | ITGA | ITGA | famplex_relations | ITGA9 | 3680 |
| Homo sapiens | Primates | ITGA | ITGA | famplex_relations | ITGAD | 3681 |
| Homo sapiens | Primates | ITGA | ITGA | famplex_relations | ITGAE | 3682 |
| Homo sapiens | Primates | ITGA | ITGA | famplex_relations | ITGAL | 3683 |
| Homo sapiens | Primates | ITGA | ITGA | famplex_relations | ITGAM | 3684 |
| Homo sapiens | Primates | ITGA | ITGA | famplex_relations | ITGAV | 3685 |
| Homo sapiens | Primates | ITGA | ITGA | famplex_relations | ITGAX | 3687 |
| Homo sapiens | Primates | ITGB | ITGB | famplex_relations | ITGB1 | 3688 |
| Homo sapiens | Primates | ITGB | ITGB | famplex_relations | ITGB2 | 3689 |
| Homo sapiens | Primates | ITGB | ITGB | famplex_relations | ITGB3 | 3690 |
| Homo sapiens | Primates | ITGB | ITGB | famplex_relations | ITGB4 | 3691 |
| Homo sapiens | Primates | ITGB | ITGB | famplex_relations | ITGB5 | 3693 |
| Homo sapiens | Primates | ITGB | ITGB | famplex_relations | ITGB6 | 3694 |
| Homo sapiens | Primates | ITGB | ITGB | famplex_relations | ITGB7 | 3695 |
| Homo sapiens | Primates | ITGB | ITGB | famplex_relations | ITGB8 | 3696 |
| Homo sapiens | Primates | ITGB | ITGB | famplex_relations | ITGBL1 | 9358 |
| Homo sapiens | Primates | ILK | ILK | ncbigene_symbol | ILK | 3611 |
| Homo sapiens | Primates | PKC | PKC | ncbigene_synonym | PRRT2 | 112476 |
| Homo sapiens | Primates | PKC | PKC | famplex_relations | PRKCA | 5578 |
| Homo sapiens | Primates | PKC | PKC | famplex_relations | PRKCB | 5579 |
| Homo sapiens | Primates | PKC | PKC | famplex_relations | PRKCD | 5580 |
| Homo sapiens | Primates | PKC | PKC | famplex_relations | PRKCE | 5581 |
| Homo sapiens | Primates | PKC | PKC | famplex_relations | PRKCG | 5582 |
| Homo sapiens | Primates | PKC | PKC | famplex_relations | PRKCH | 5583 |
| Homo sapiens | Primates | PKC | PKC | famplex_relations | PRKCI | 5584 |
| Homo sapiens | Primates | PKC | PKC | famplex_relations | PRKCQ | 5588 |
| Homo sapiens | Primates | PKC | PKC | famplex_relations | PRKCZ | 5590 |
| Homo sapiens | Primates | PKC | PKC | famplex_relations | PRKD3 | 23683 |
| Homo sapiens | Primates | PTEN | PTEN | ncbigene_symbol | PTEN | 5728 |
| Homo sapiens | Primates | FAK | FAK | ncbigene_synonym | PTK2 | 5747 |
| Homo sapiens | Primates | PI3K | PI3K | ncbigene_synonym | PIK3CA | 5290 |
| Homo sapiens | Primates | PI3K | PI3K | ncbigene_synonym | PIK3CB | 5291 |
| Homo sapiens | Primates | PI3K | PI3K | ncbigene_synonym | PIK3CD | 5293 |
| Homo sapiens | Primates | PI3K | PI3K | ncbigene_synonym | PIK3CG | 5294 |
| Homo sapiens | Primates | PI3K | PI3K | famplex_relations | PIK3R3 | 8503 |
| Homo sapiens | Primates | PI3K | PI3K | famplex_relations | PIK3R4 | 30849 |
| Homo sapiens | Primates | PI3K | PI3K | famplex_relations | PIK3R5 | 23533 |
| Homo sapiens | Primates | PI3K | PI3K | famplex_relations | PIK3R6 | 146850 |
| Homo sapiens | Primates | PI3K | PI3K | famplex_relations | PIK3R1 | 5295 |
| Homo sapiens | Primates | PI3K | PI3K | famplex_relations | PIK3R2 | 5296 |
| Homo sapiens | Primates | actin | ACTIN | famplex_relations | ACTA1 | 58 |
| Homo sapiens | Primates | actin | ACTIN | famplex_relations | ACTA2 | 59 |
| Homo sapiens | Primates | actin | ACTIN | famplex_relations | ACTB | 60 |
| Homo sapiens | Primates | actin | ACTIN | famplex_relations | ACTC1 | 70 |
| Homo sapiens | Primates | actin | ACTIN | famplex_relations | ACTG1 | 71 |
| Homo sapiens | Primates | actin | ACTIN | famplex_relations | ACTG2 | 72 |
| Homo sapiens | Primates | Steps | STEP | ncbigene_synonym | PTPN5 | 84867 |
| Homo sapiens | Primates | ask | ASK | ncbigene_synonym | DBF4 | 10926 |
| Homo sapiens | Primates | Cdc42 | CDC42 | ncbigene_symbol | CDC42 | 998 |
| Homo sapiens | Primates | Wnt | WNT | famplex_relations | WNT1 | 7471 |
| Homo sapiens | Primates | Wnt | WNT | famplex_relations | WNT2 | 7472 |
| Homo sapiens | Primates | Wnt | WNT | famplex_relations | WNT2B | 7482 |
| Homo sapiens | Primates | Wnt | WNT | famplex_relations | WNT3 | 7473 |
| Homo sapiens | Primates | Wnt | WNT | famplex_relations | WNT3A | 89780 |
| Homo sapiens | Primates | Wnt | WNT | famplex_relations | WNT4 | 54361 |
| Homo sapiens | Primates | Wnt | WNT | famplex_relations | WNT6 | 7475 |
| Homo sapiens | Primates | Wnt | WNT | famplex_relations | WNT7A | 7476 |
| Homo sapiens | Primates | Wnt | WNT | famplex_relations | WNT7B | 7477 |
| Homo sapiens | Primates | Wnt | WNT | famplex_relations | WNT8A | 7478 |
| Homo sapiens | Primates | Wnt | WNT | famplex_relations | WNT8B | 7479 |
| Homo sapiens | Primates | Wnt | WNT | famplex_relations | WNT9A | 7483 |
| Homo sapiens | Primates | Wnt | WNT | famplex_relations | WNT9B | 7484 |
| Homo sapiens | Primates | Wnt | WNT | famplex_relations | WNT10A | 80326 |
| Homo sapiens | Primates | Wnt | WNT | famplex_relations | WNT10B | 7480 |
| Homo sapiens | Primates | Wnt | WNT | famplex_relations | WNT11 | 7481 |
| Homo sapiens | Primates | Wnt | WNT | famplex_relations | WNT16 | 51384 |
| Homo sapiens | Primates | Wnt | WNT | famplex_relations | WNT5A | 7474 |
| Homo sapiens | Primates | Wnt | WNT | famplex_relations | WNT5B | 81029 |
| Homo sapiens | Primates | Rac | RAC | ncbigene_synonym | AKT1 | 207 |
| Homo sapiens | Primates | Rac | RAC | famplex_relations | RAC1 | 5879 |
| Homo sapiens | Primates | Rac | RAC | famplex_relations | RAC2 | 5880 |
| Homo sapiens | Primates | Rac | RAC | famplex_relations | RAC3 | 5881 |
| Homo sapiens | Primates | Rac | RAC | famplex_relations | RHOG | 391 |
| Homo sapiens | Primates | PAK | PAK | famplex_relations | PAK1 | 5058 |
| Homo sapiens | Primates | PAK | PAK | famplex_relations | PAK2 | 5062 |
| Homo sapiens | Primates | PAK | PAK | famplex_relations | PAK3 | 5063 |
| Homo sapiens | Primates | PAK | PAK | famplex_relations | PAK4 | 10298 |
| Homo sapiens | Primates | PAK | PAK | famplex_relations | PAK5 | 57144 |
| Homo sapiens | Primates | PAK | PAK | famplex_relations | PAK6 | 56924 |
| Homo sapiens | Primates | Crk | CRK | ncbigene_symbol | CRK | 1398 |
| Homo sapiens | Primates | Rap | RAP | ncbigene_synonym | LRPAP1 | 4043 |
| Homo sapiens | Primates | JNK | JNK | ncbigene_synonym | MAPK8 | 5599 |
| Homo sapiens | Primates | JNK | JNK | famplex_relations | MAPK9 | 5601 |
| Homo sapiens | Primates | JNK | JNK | famplex_relations | MAPK10 | 5602 |
| Homo sapiens | Primates | B-Raf | B-RAF | ncbigene_synonym | BRAF | 673 |
| Homo sapiens | Primates | ttp | TTP | ncbigene_synonym | ZFP36 | 7538 |
| Homo sapiens | Primates | ttp | TTP | ncbigene_synonym | SH3BP4 | 23677 |
| Homo sapiens | Primates | She | SHE | ncbigene_symbol | SHE | 126669 |
| Homo sapiens | Primates | Sos | SOS | ncbigene_synonym | XYLT2 | 64132 |
| Homo sapiens | Primates | Sos | SOS | famplex_relations | SOS1 | 6654 |
| Homo sapiens | Primates | Sos | SOS | famplex_relations | SOS2 | 6655 |
| Homo sapiens | Primates | Raf-1 | RAF-1 | ncbigene_synonym | RAF1 | 5894 |
| Homo sapiens | Primates | clAPs | CLAP | ncbigene_synonym | BCL10 | 8915 |
| Homo sapiens | Primates | Bad | BAD | ncbigene_symbol | BAD | 572 |
| Word | Match | MeSH | Name | ChEBI |
|---|---|---|---|---|
| PIP3 | PIP3 | 1-O-(3-sn-phosphatidyl)-1D-myo-inositol 3,4,5-tris(dihydrogen phosphate) | chebi:16618 | |
| DNA | DNA | deoxyribonucleic acids | chebi:16991 | |
| ttp | TTP | 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-[2-(triphosphooxy)ethyl]-4-methyl-1,3-thiazol-3-ium | chebi:9534 | |
| DNA | DNA | deoxyribonucleic acids | chebi:16991 |
Disease mentions
| Word | Match | MeSH | Name | DOID |
|---|